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Opposite Effects of Src Family Kinases on YAP and ERK Activation in Pancreatic Cancer Cells: Implications for Targeted Therapy

Pancreatic ductal adenocarcinoma (PDAC) remains an aggressive disease that is expected to become the second cause of cancer fatalities during the next decade. As therapeutic options are limited, novel targets, and agents for therapeutic intervention are urgently needed. Previously, we identified pot...

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Detalles Bibliográficos
Autores principales: Sinnett-Smith, James, Anwar, Tarique, Reed, Elaine F., Teper, Yaroslav, Eibl, Guido, Rozengurt, Enrique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9630827/
https://www.ncbi.nlm.nih.gov/pubmed/35999654
http://dx.doi.org/10.1158/1535-7163.MCT-21-0964