Cargando…

Schisandrin B Attenuates Diabetic Cardiomyopathy by Targeting MyD88 and Inhibiting MyD88‐Dependent Inflammation

Diabetes manifests as chronic inflammation and leads to the development diabetic cardiomyopathy (DCM). Targeting key proteins in inflammatory signaling may provide new therapy for DCM. In this study, the authors explore the pharmacological effects and mechanisms of Schisandrin B (Sch B), a natural c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Luo, Wu, Lin, Ke, Hua, Junyi, Han, Jibo, Zhang, Qiuyan, Chen, Lingfeng, Khan, Zia A., Wu, Gaojun, Wang, Yi, Liang, Guang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9631063/ https://www.ncbi.nlm.nih.gov/pubmed/36180407 http://dx.doi.org/10.1002/advs.202202590

Ejemplares similares

Soyasaponins reduce inflammation by downregulating MyD88 expression and suppressing the recruitments of TLR4 and MyD88 into lipid rafts
por: Chen, Junbin, et al.
Publicado: (2020)

MyD88 and beyond: a perspective on MyD88-targeted therapeutic approach for modulation of host immunity
por: Saikh, Kamal U.
Publicado: (2021)

MyD88 deficiency aggravates the severity of acute pancreatitis by promoting MyD88-independent TRIF pathway-mediated necrosis
por: Yang, Du-Jiang, et al.
Publicado: (2022)

A MyD88 meddles with survival
por: Bashyam, Hema
Publicado: (2007)

Role of MyD88 in Adenovirus Keratitis
por: Zhou, Xiaohong, et al.
Publicado: (2016)

Mucus clearance, MyD88-dependent and MyD88-independent immunity modulate lung susceptibility to spontaneous bacterial infection and inflammation
por: Livraghi-Butrico, Alessandra, et al.
Publicado: (2012)

MyD88 contribution to ocular surface homeostasis
por: Reins, Rose Y., et al.
Publicado: (2017)

Mechanism of MyD88S mediated signal termination
por: Pustelny, Katarzyna, et al.
Publicado: (2022)

A Novel Kindred with MyD88 Deficiency
por: Bucciol, Giorgia, et al.
Publicado: (2022)

MyD88 Polymorphisms and Association with Susceptibility to Salmonella Pullorum
por: Liu, Xian-Qing, et al.
Publicado: (2015)

Ischemia-Reperfusion Lung Injury Is Attenuated in MyD88-Deficient Mice
por: Altemeier, William A., et al.
Publicado: (2013)

Lipopolysaccharide-induced NF-κB nuclear translocation is primarily dependent on MyD88, but TNFα expression requires TRIF and MyD88
por: Sakai, Jiro, et al.
Publicado: (2017)

Identification and Function of Myeloid Differentiation Factor 88 (MyD88) in Litopenaeus vannamei
por: Zhang, Shuang, et al.
Publicado: (2012)

Hepatic MyD88 regulates liver inflammation by altering synthesis of oxysterols
por: Lefort, Charlotte, et al.
Publicado: (2019)

Harnessing the Antiinflammatory Power of MyD88 to Reduce Allergic Fungal Inflammation?
por: Gaurav, Rohit, et al.
Publicado: (2021)

LCZ696 Attenuated Doxorubicin-Induced Chronic Cardiomyopathy Through the TLR2-MyD88 Complex Formation
por: Ye, Shiju, et al.
Publicado: (2021)

MyD88 predicts chemoresistance to paclitaxel in epithelial ovarian cancer
por: Silasi, Dan-Arin, et al.
Publicado: (2007)

Alternative activation of macrophages by filarial nematodes is MyD88-independent
por: Mylonas, Katie J., et al.
Publicado: (2013)

MyD88-Dependent Pathways in Leukocytes Affect the Retina in Diabetes
por: Tang, Jie, et al.
Publicado: (2013)

MyD88: a central player in innate immune signaling
por: Deguine, Jacques, et al.
Publicado: (2014)

MyD88 and TLR4 Expression in Epithelial Ovarian Cancer
por: Block, Matthew S., et al.
Publicado: (2018)

MyD88 signalling is critical in the development of pancreatic cancer cachexia
por: Zhu, Xinxia, et al.
Publicado: (2019)

Inflammatory Role of TLR-MyD88 Signaling in Multiple Sclerosis
por: Zheng, Chao, et al.
Publicado: (2020)

Possible Involvement of MyD88 in Regulating Stress Response in Mice
por: Hosoi, Toru, et al.
Publicado: (2021)

Myeloid Differentiation Factor 88 (MyD88)-Deficiency Increases Risk of Diabetes in Mice
por: Hosoi, Toru, et al.
Publicado: (2010)

Selective disruption of TLR2-MyD88 interaction inhibits inflammation and attenuates Alzheimer’s pathology
por: Rangasamy, Suresh B., et al.
Publicado: (2018)

Function of astrocyte MyD88 in high-fat-diet-induced hypothalamic inflammation
por: Jin, Sungho, et al.
Publicado: (2020)

IL-1R–MyD88 signaling in keratinocyte transformation and carcinogenesis
por: Cataisson, Christophe, et al.
Publicado: (2012)

The MyD88+ Phenotype Is an Adverse Prognostic Factor in Epithelial Ovarian Cancer
por: d'Adhemar, Charles J., et al.
Publicado: (2014)

Beyond MyD88 and TRIF Pathways in Toll-Like Receptor Signaling
por: Piras, Vincent, et al.
Publicado: (2014)

MyD88 promotes myoblast fusion in a cell-autonomous manner
por: Hindi, Sajedah M., et al.
Publicado: (2017)

Induction of Hypergammaglobulinemia and Autoantibodies by Salmonella Infection in MyD88-Deficient Mice
por: Issac, Jincy M., et al.
Publicado: (2018)

MyD88 Deficiency Protects Against Dry Eye–Induced Damage
por: Reins, Rose Y., et al.
Publicado: (2018)

MyD88 Is Required for Efficient Control of Coxiella burnetii Infection and Dissemination
por: Kohl, Lisa, et al.
Publicado: (2019)

MyD88 Mediates Colitis- and RANKL-Induced Microfold Cell Differentiation
por: Li, Yang, et al.
Publicado: (2021)

Evolution of Toll, Spatzle and MyD88 in insects: the problem of the Diptera bias
por: Lima, Letícia Ferreira, et al.
Publicado: (2021)

From monogenic lupus to TLR7/MyD88-targeted therapy
por: Wang, Min, et al.
Publicado: (2022)

Distinct Cell-specific Roles of NOX2 and MyD88 in Epileptogenesis
por: Almeida, Cayo, et al.
Publicado: (2022)

Two Human MYD88 Variants, S34Y and R98C, Interfere with MyD88-IRAK4-Myddosome Assembly
por: George, Julie, et al.
Publicado: (2011)

MyD88-dependent, superoxide-initiated inflammation is necessary for flow-mediated inward remodeling of conduit arteries
por: Tang, Paul C.Y., et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_b4qmefraih8da0l061ra2o2nu7