Patient‐Derived Organoids from Colorectal Cancer with Paired Liver Metastasis Reveal Tumor Heterogeneity and Predict Response to Chemotherapy

There is no effective method to predict chemotherapy response and postoperative prognosis of colorectal cancer liver metastasis (CRLM) patients. Patient‐derived organoid (PDO) has become an important preclinical model. Herein, a living biobank with 50 CRLM organoids derived from primary tumors and p...

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Detalles Bibliográficos
Autores principales: Mo, Shaobo, Tang, Peiyuan, Luo, Wenqin, Zhang, Long, Li, Yaqi, Hu, Xiang, Ma, Xiaoji, Chen, Yikuan, Bao, Yichao, He, Xingfeng, Fu, Guoxiang, Xu, Xiaoya, Rao, Xinxin, Li, Xiaomeng, Guan, Ruoyu, Chen, Shengzhi, Deng, Yun, Lv, Tao, Mu, Peiyuan, Zheng, Qiang, Wang, Simin, Liu, Fangqi, Li, Yiwei, Sheng, Weiqi, Huang, Dan, Hu, Chen, Gao, Jianjun, Zhang, Zhen, Cai, Sanjun, Clevers, Hans, Peng, Junjie, Hua, Guoqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9631073/
https://www.ncbi.nlm.nih.gov/pubmed/36058001
http://dx.doi.org/10.1002/advs.202204097

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