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Spontaneous remission of hepatic myelopathy in a patient with alcoholic cirrhosis: A case report

BACKGROUND: Hepatic myelopathy (HM) is a rare neurological complication of advanced cirrhosis. Prognosis of patients with HM is generally poor without timely liver transplantation or interventional therapy. Self-resolving HM in patients with alcoholic cirrhosis has never been reported. CASE SUMMARY:...

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Autores principales: Chang, Chun-Yan, Liu, Chen, Duan, Fang-Fang, Zhai, Hang, Song, Shan-Shan, Yang, Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9631124/
https://www.ncbi.nlm.nih.gov/pubmed/36338225
http://dx.doi.org/10.12998/wjcc.v10.i30.11172
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author Chang, Chun-Yan
Liu, Chen
Duan, Fang-Fang
Zhai, Hang
Song, Shan-Shan
Yang, Song
author_facet Chang, Chun-Yan
Liu, Chen
Duan, Fang-Fang
Zhai, Hang
Song, Shan-Shan
Yang, Song
author_sort Chang, Chun-Yan
collection PubMed
description BACKGROUND: Hepatic myelopathy (HM) is a rare neurological complication of advanced cirrhosis. Prognosis of patients with HM is generally poor without timely liver transplantation or interventional therapy. Self-resolving HM in patients with alcoholic cirrhosis has never been reported. CASE SUMMARY: A 53-year-old man with alcoholic cirrhosis and recurrent overt hepatic encephalopathy for 1 year was admitted for lower extremity weakness, slow movement, and stumbling gait. The patient was diagnosed with HM after excluding other causes of spastic paraparesis. The patient refused liver transplantation. However, the patient kept total abstinence and received a multidisciplinary treatment for complications of decompensated cirrhosis. The symptoms of HM resolved gradually after 2 years of treatment. All complications of alcoholic cirrhosis resolved after 4 years of follow-up. CONCLUSION: The case demonstrates that HM can resolve in patients without liver transplan-tation after total abstinence and systemic management of complications.
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spelling pubmed-96311242022-11-04 Spontaneous remission of hepatic myelopathy in a patient with alcoholic cirrhosis: A case report Chang, Chun-Yan Liu, Chen Duan, Fang-Fang Zhai, Hang Song, Shan-Shan Yang, Song World J Clin Cases Case Report BACKGROUND: Hepatic myelopathy (HM) is a rare neurological complication of advanced cirrhosis. Prognosis of patients with HM is generally poor without timely liver transplantation or interventional therapy. Self-resolving HM in patients with alcoholic cirrhosis has never been reported. CASE SUMMARY: A 53-year-old man with alcoholic cirrhosis and recurrent overt hepatic encephalopathy for 1 year was admitted for lower extremity weakness, slow movement, and stumbling gait. The patient was diagnosed with HM after excluding other causes of spastic paraparesis. The patient refused liver transplantation. However, the patient kept total abstinence and received a multidisciplinary treatment for complications of decompensated cirrhosis. The symptoms of HM resolved gradually after 2 years of treatment. All complications of alcoholic cirrhosis resolved after 4 years of follow-up. CONCLUSION: The case demonstrates that HM can resolve in patients without liver transplan-tation after total abstinence and systemic management of complications. Baishideng Publishing Group Inc 2022-10-26 2022-10-26 /pmc/articles/PMC9631124/ /pubmed/36338225 http://dx.doi.org/10.12998/wjcc.v10.i30.11172 Text en ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. https://creativecommons.org/licenses/by-nc/4.0/This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
spellingShingle Case Report
Chang, Chun-Yan
Liu, Chen
Duan, Fang-Fang
Zhai, Hang
Song, Shan-Shan
Yang, Song
Spontaneous remission of hepatic myelopathy in a patient with alcoholic cirrhosis: A case report
title Spontaneous remission of hepatic myelopathy in a patient with alcoholic cirrhosis: A case report
title_full Spontaneous remission of hepatic myelopathy in a patient with alcoholic cirrhosis: A case report
title_fullStr Spontaneous remission of hepatic myelopathy in a patient with alcoholic cirrhosis: A case report
title_full_unstemmed Spontaneous remission of hepatic myelopathy in a patient with alcoholic cirrhosis: A case report
title_short Spontaneous remission of hepatic myelopathy in a patient with alcoholic cirrhosis: A case report
title_sort spontaneous remission of hepatic myelopathy in a patient with alcoholic cirrhosis: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9631124/
https://www.ncbi.nlm.nih.gov/pubmed/36338225
http://dx.doi.org/10.12998/wjcc.v10.i30.11172
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