Dysmegakaryopoiesis and Transient Mild Increase in Bone Marrow Blasts in Patients With Aplastic Anemia Treated With Eltrombopag May Be Signs of Hematologic Improvement and Not Portend Clonal Evolution

OBJECTIVES: Eltrombopag, a thrombopoietin-receptor agonist, stimulates hematopoiesis in patients with acquired aplastic anemia (AA). Cytomorphologic changes in bone marrow after eltrombopag administration are still unclear. This study examined the effect of eltrombopag on cytomorphologic findings us...

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Detalles Bibliográficos
Autores principales: Matsuda, Akira, Imada, Kazunori, Obara, Naoshi, Iida, Hiroatsu, Yamazaki, Hirohito, Tomiyama, Yoshiaki, Miyamura, Koichi, Sasaki, Osamu, Maeda, Tetsuo, Ohta, Kensuke, Usuki, Kensuke, Tokumine, Yukihiro, Imajo, Kenji, Okamoto, Yuji, Murakami, Mami, Nakao, Shinji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9631234/
https://www.ncbi.nlm.nih.gov/pubmed/36018052
http://dx.doi.org/10.1093/ajcp/aqac094

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