Research progress on microRNA in gout

Gout is a common form of arthritis caused by the deposition of sodium urate crystals in the joints and tissues around them. MicroRNAs (miRNAs) are noncoding RNAs that have been shown to be involved in regulating the pathogenesis of gout through multiple cellular signaling pathways, which may be pote...

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Detalles Bibliográficos
Autores principales: Xie, Jing, He, Cuixia, Su, Yue, Ding, Yuzhou, Zhu, Xingyu, Xu, Yuanyuan, Ding, Jiaxiang, Zhou, Huan, Wang, Hongju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9631428/
https://www.ncbi.nlm.nih.gov/pubmed/36339582
http://dx.doi.org/10.3389/fphar.2022.981799
Descripción
Sumario:Gout is a common form of arthritis caused by the deposition of sodium urate crystals in the joints and tissues around them. MicroRNAs (miRNAs) are noncoding RNAs that have been shown to be involved in regulating the pathogenesis of gout through multiple cellular signaling pathways, which may be potential targets for the treatment of gout. In this review, we systematically discuss the regulatory roles of related miRNAs in gout, which will provide help for the treatment of gout and miRNAs is expected to become a potential biomarker for gout diagnosis.

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