CEACAM1 is a novel culture-compatible surface marker of expanded long-term reconstituting hematopoietic stem cells

CEACAM1 is a novel cell surface marker of ex vivo expanded LT-HSCs. Sorting umbilical cord blood cells based on CEACAM1 and known HSC marker expression allows purification of LT-HSCs with improved purity.

Detalles Bibliográficos
Autores principales: Ansari, Unain, Tomellini, Elisa, Chagraoui, Jalila, Lehnertz, Bernhard, Mayotte, Nadine, Bordeleau, Marie-Eve, Roux, Philippe P., Sauvageau, Guy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2022
Materias:
Stimulus Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9631550/
https://www.ncbi.nlm.nih.gov/pubmed/35286394
http://dx.doi.org/10.1182/bloodadvances.2021006835
Descripción
Sumario:CEACAM1 is a novel cell surface marker of ex vivo expanded LT-HSCs. Sorting umbilical cord blood cells based on CEACAM1 and known HSC marker expression allows purification of LT-HSCs with improved purity.

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