ATG4A regulates human erythroid maturation and mitochondrial clearance

Autophagy is a self-degradation pathway that is essential for erythropoiesis. During erythroid differentiation, autophagy facilitates the degradation of macromolecules and the programmed clearance of mitochondria. Impaired mitochondrial clearance results in anemia and alters the lifespan of red bloo...

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Detalles Bibliográficos
Autores principales: Stolla, Massiel Chavez, Reilly, Andreea, Bergantinos, Rochelle, Stewart, Sintra, Thom, Neele, Clough, Courtnee A., Wellington, Rachel C., Stolitenko, Raisa, Abkowitz, Janis L., Doulatov, Sergei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2022
Materias:
Red Cells, Iron, and Erythropoiesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9631553/
https://www.ncbi.nlm.nih.gov/pubmed/35443024
http://dx.doi.org/10.1182/bloodadvances.2021005910

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9631553/
https://www.ncbi.nlm.nih.gov/pubmed/35443024
http://dx.doi.org/10.1182/bloodadvances.2021005910

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