HSCT using carrier donors for CD40L deficiency results in excellent immune function and higher CD40L expression in cTfh

Data are limited regarding the immune status of CD40 ligand (CD40L)–deficient carriers and hematopoietic stem cell transplantation (HSCT) outcomes using them as donors for CD40L-deficient patients. Therefore, we studied the immune profiles of 7 carriers, 4 of whom were HSCT donors for family members...

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Detalles Bibliográficos
Autores principales: Chandrakasan, Shanmuganathan, Chandra, Sharat, Prince, Chengyu, Kobrynski, Lisa J., Lucas, Laura, Patel, Kiran, Walter, Jolan, Buckley, Rebecca H., Meisel, Roland, Ghosh, Sujal, Parikh, Suhag H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2022
Materias:
Stimulus Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9631566/
https://www.ncbi.nlm.nih.gov/pubmed/35443026
http://dx.doi.org/10.1182/bloodadvances.2021006905

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