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Production and Characterization of Human Monoclonal Antibody Fab Fragments to Vaccinia Virus from a Phage-Display Combinatorial Library()

A combinatorial, phage-display library of human Fab antibody fragments was generated from IgG heavy chain (HC) and light chain (LC) genes cloned from the lymphocytes of a vaccinia virus (VACV)-immune donor. To ascertain the complexity of the library, nucleotide sequences of the variable regions of t...

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Detalles Bibliográficos
Autores principales:	Schmaljohn, Connie, Cui, Yunchang, Kerby, Stephen, Pennock, David, Spik, Kristin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Published by Elsevier Inc. 1999
Materias:	Regular Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9631611/ https://www.ncbi.nlm.nih.gov/pubmed/10329580 http://dx.doi.org/10.1006/viro.1999.9701

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