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Linked-read whole-genome sequencing resolves common and private structural variants in multiple myeloma

Multiple myeloma (MM) is an incurable and aggressive plasma cell malignancy characterized by a complex karyotype with multiple structural variants (SVs) and copy-number variations (CNVs). Linked-read whole-genome sequencing (lrWGS) allows for refined detection and reconstruction of SVs by providing...

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Detalles Bibliográficos
Autores principales:	Peña-Pérez, Lucía, Frengen, Nicolai, Hauenstein, Julia, Gran, Charlotte, Gustafsson, Charlotte, Eisfeldt, Jesper, Kierczak, Marcin, Taborsak-Lines, Fanny, Olsen, Remi-André, Wallblom, Ann, Krstic, Aleksandra, Ewels, Philip, Lindstrand, Anna, Månsson, Robert
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Hematology 2022
Materias:	Lymphoid Neoplasia
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9631623/ https://www.ncbi.nlm.nih.gov/pubmed/35675515 http://dx.doi.org/10.1182/bloodadvances.2021006720

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