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Invariant NKT cells dictate antitumor immunity elicited by a bispecific antibody cotargeting CD3 and BCMA
CD3-engaging bispecific antibodies (BsAbs) have emerged as powerful therapeutic approaches by their ability to redirect T cells to eliminate tumor cells in a major histocompatibility complex–independent manner. However, how we can potentiate the efficacy of BsAbs remains largely unknown. To address...
Autores principales: | Casey, Mika, Tu, Cui, Harrison, Simon J., Nakamura, Kyohei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Hematology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9631633/ https://www.ncbi.nlm.nih.gov/pubmed/35830292 http://dx.doi.org/10.1182/bloodadvances.2022008118 |
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