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Siltuximab is associated with improved progression-free survival in idiopathic multicentric Castleman disease
Idiopathic multicentric Castleman disease (iMCD) is a rare heterogeneous disorder involving multicentric lymphadenopathy, systemic inflammation, and cytokine-driven organ dysfunction. Despite the approval of siltuximab, a monoclonal antibody against interleukin-6, for the treatment of iMCD, it is no...
Autores principales: | van Rhee, Frits, Rosenthal, Adam, Kanhai, Karan, Martin, Rabecka, Nishimura, Katherine, Hoering, Antje, Fajgenbaum, David C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Hematology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9631655/ https://www.ncbi.nlm.nih.gov/pubmed/35793409 http://dx.doi.org/10.1182/bloodadvances.2022007112 |
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