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Cytokine pathway variants modulate platelet production: IFNA16 is a thrombocytosis susceptibility locus in humans
Inflammatory stimuli have divergent effects on peripheral platelet counts, although the mechanisms of thrombocytopenic and thrombocytotic responses remain poorly understood. A candidate gene approach targeting 326 polymorphic genes enriched in thrombopoietic and cytokine signaling pathways was appli...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Hematology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9631663/ https://www.ncbi.nlm.nih.gov/pubmed/35381074 http://dx.doi.org/10.1182/bloodadvances.2021005648 |