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Cytokine pathway variants modulate platelet production: IFNA16 is a thrombocytosis susceptibility locus in humans

Inflammatory stimuli have divergent effects on peripheral platelet counts, although the mechanisms of thrombocytopenic and thrombocytotic responses remain poorly understood. A candidate gene approach targeting 326 polymorphic genes enriched in thrombopoietic and cytokine signaling pathways was appli...

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Detalles Bibliográficos
Autores principales:	Gnatenko, Dmitri V., Liu, Zhaoyan, Hearing, Patrick, Sohn, Sook-Young, Hu, Yetao, Falanga, Anna, Wu, Song, Malone, Lisa E., Zhu, Wei, Bahou, Wadie F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Hematology 2022
Materias:	Platelets and Thrombopoiesis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9631663/ https://www.ncbi.nlm.nih.gov/pubmed/35381074 http://dx.doi.org/10.1182/bloodadvances.2021005648

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