Cargando…

Aberrant brain functional and structural developments in MECP2 duplication rats

Transgenic animal models with homologous etiology provide a promising way to pursue the neurobiological substrates of the behavioral deficits in autism spectrum disorder (ASD). Gain-of-function mutations of MECP2 cause MECP2 duplication syndrome, a severe neurological disorder with core symptoms of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xu, Ming, Qi, Shile, Calhoun, Vince, Dai, Jiankun, Yu, Bin, Zhang, Kaiwei, Pei, Mengchao, Li, Chenjian, Wei, Yusheng, Jiang, Rongtao, Zhi, Dongmei, Huang, Zhimin, Qiu, Zilong, Liang, Zhifeng, Sui, Jing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9631682/ https://www.ncbi.nlm.nih.gov/pubmed/35985556 http://dx.doi.org/10.1016/j.nbd.2022.105838

Ejemplares similares

Aberrant Dynamic Functional Network Connectivity and Graph Properties in Major Depressive Disorder
por: Zhi, Dongmei, et al.
Publicado: (2018)

Altered visual cortical processing in a mouse model of MECP2 duplication syndrome
por: Zhang, Dinghong, et al.
Publicado: (2017)

Common and unique multimodal covarying patterns in autism spectrum disorder subtypes
por: Qi, Shile, et al.
Publicado: (2020)

Medical Comorbidities in MECP2 Duplication Syndrome: Results from the International MECP2 Duplication Database
por: Ta, Daniel, et al.
Publicado: (2022)

Duplication within two regions distal to MECP2: clinical similarity with MECP2 duplication syndrome
por: Akahoshi, Keiko, et al.
Publicado: (2023)

Three‐way parallel group independent component analysis: Fusion of spatial and spatiotemporal magnetic resonance imaging data
por: Qi, Shile, et al.
Publicado: (2021)

Associations between grip strength, brain structure, and mental health in > 40,000 participants from the UK Biobank
por: Jiang, Rongtao, et al.
Publicado: (2022)

Rett Syndrome and MECP2 Duplication Syndrome: Disorders of MeCP2 Dosage
por: Collins, Bridget E, et al.
Publicado: (2022)

Accumulated quiescent neural stem cells in adult hippocampus of the mouse model for the MECP2 duplication syndrome
por: Chen, Zhifang, et al.
Publicado: (2017)

Task-induced brain connectivity promotes the detection of individual differences in brain-behavior relationships
por: Jiang, Rongtao, et al.
Publicado: (2019)

NR4A1 Methylation Associated Multimodal Neuroimaging Patterns Impaired in Temporal Lobe Epilepsy
por: Zhi, Dongmei, et al.
Publicado: (2020)

A Neuroimaging Signature of Cognitive Aging from Whole‐Brain Functional Connectivity
por: Jiang, Rongtao, et al.
Publicado: (2022)

MECP2 duplication syndrome in a Chinese family
por: Zhang, Qingping, et al.
Publicado: (2015)

Infectious and Immunologic Phenotype of MECP2 Duplication Syndrome
por: Bauer, Michael, et al.
Publicado: (2015)

Elevated C-reactive protein mediates the liver-brain axis: a preliminary study
por: Jiang, Rongtao, et al.
Publicado: (2023)

Cortisol profiles and clinical severity in MECP2 duplication syndrome
por: Peters, Sarika U., et al.
Publicado: (2020)

A partial MECP2 duplication in a mildly affected adult male: a putative role for the 3' untranslated region in the MECP2 duplication phenotype
por: Hanchard, Neil A, et al.
Publicado: (2012)

Electroconvulsive therapy treatment responsive multimodal brain networks
por: Qi, Shile, et al.
Publicado: (2020)

A case report of Chinese brothers with inherited MECP2-containing duplication: autism and intellectual disability, but not seizures or respiratory infections
por: Xu, Xiu, et al.
Publicado: (2012)

Associations of physical frailty with health outcomes and brain structure in 483 033 middle-aged and older adults: a population-based study from the UK Biobank
por: Jiang, Rongtao, et al.
Publicado: (2023)

The relevance of transdiagnostic shared networks to the severity of symptoms and cognitive deficits in schizophrenia: a multimodal brain imaging fusion study
por: Qi, Shile, et al.
Publicado: (2020)

Reversal of phenotypes in MECP2 duplication mice using genetic rescue or antisense oligos
por: Sztainberg, Yehezkel, et al.
Publicado: (2015)

Rett-causing mutations reveal two domains critical for MeCP2 function and for toxicity in MECP2 duplication syndrome mice
por: Heckman, Laura Dean, et al.
Publicado: (2014)

MECP2 duplication phenotype in symptomatic females: report of three further cases
por: Novara, Francesca, et al.
Publicado: (2014)

Altered neuronal network and rescue in a human MECP2 duplication model
por: Nageshappa, Savitha, et al.
Publicado: (2015)

Rett mutations attenuate phase separation of MeCP2
por: Fan, Chunyan, et al.
Publicado: (2020)

Preliminary prediction of individual response to electroconvulsive therapy using whole-brain functional magnetic resonance imaging data
por: Sun, Hailun, et al.
Publicado: (2019)

IRAK1 Duplication in MECP2 Duplication Syndrome Does Not Increase Canonical NF-κB–Induced Inflammation
por: Gottschalk, Ilona, et al.
Publicado: (2022)

Regulation of mRNA splicing by MeCP2 via epigenetic modifications in the brain
por: Cheng, Tian-Lin, et al.
Publicado: (2017)

Exploring the Psychosis Functional Connectome: Aberrant Intrinsic Networks in Schizophrenia and Bipolar Disorder
por: Calhoun, Vince D, et al.
Publicado: (2012)

Gender Differences in Connectome-based Predictions of Individualized Intelligence Quotient and Sub-domain Scores
por: Jiang, Rongtao, et al.
Publicado: (2020)

Cognition, Aryl Hydrocarbon Receptor Repressor Methylation, and Abstinence Duration-Associated Multimodal Brain Networks in Smoking and Long-Term Smoking Cessation
por: Qi, Shile, et al.
Publicado: (2022)

MeCP2 duplication causes hyperandrogenism by upregulating LHCGR and downregulating RORα
por: Wang, Yu-Meng, et al.
Publicado: (2021)

MECP2 duplication syndrome: The electroclinical features of a case with long-term evolution
por: Cani, Ilaria, et al.
Publicado: (2022)

A brief history of MECP2 duplication syndrome: 20-years of clinical understanding
por: Ta, Daniel, et al.
Publicado: (2022)

MECP2 duplication syndrome initially misdiagnosed as cerebral palsy: a case report
por: Kim, Tae-Yong, et al.
Publicado: (2023)

How Families Manage the Complex Medical Needs of Their Children with MECP2 Duplication Syndrome
por: John Cherian, Dani, et al.
Publicado: (2023)

Functional Imaging Derived ADHD Biotypes Based on Deep Clustering May Guide Personalized Medication Therapy
por: Feng, Aichen, et al.
Publicado: (2023)

Identification of autism-related MECP2 mutations by whole-exome sequencing and functional validation
por: Wen, Zhu, et al.
Publicado: (2017)

Multimodal brain deficits shared in early‐onset and adult‐onset schizophrenia predict positive symptoms regardless of illness stage
por: Feng, Aichen, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_86c7ilkk213ioh1nq2ist8g0rj