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N-terminal Domain of Amyloid-β Impacts Fibrillation and Neurotoxicity

[Image: see text] Alzheimer’s disease is characterized by the presence of distinct amyloid-β peptide (Aβ) assemblies with diverse sizes, shapes, and toxicity. However, the primary determinants of Aβ aggregation and neurotoxicity remain unknown. Here, the N-terminal amino acid residues of Aβ42 that d...

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Detalles Bibliográficos
Autores principales: Shi, Jing-Ming, Li, Hai-Yun, Liu, Hang, Zhu, Li, Guo, Yi-Bo, Pei, Jie, An, Hao, Li, Yan-Song, Li, Sha-Di, Zhang, Ze-Yu, Zheng, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9631750/
https://www.ncbi.nlm.nih.gov/pubmed/36340079
http://dx.doi.org/10.1021/acsomega.2c04583

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