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Whole-slide image analysis identifies a high content of Hodgkin Reed-Sternberg cells and a low content of T lymphocytes in tumor microenvironment as predictors of adverse outcome in patients with classic Hodgkin lymphoma treated with ABVD

Classic Hodgkin lymphoma (cHL) constitutes the most frequent lymphoma in young adults. Its histopathology is unique as a scattered tumor population, termed Hodgkin Reed-Sternberg (HRS) cells is diluted in a prominent tumor microenvironment (TME) composed of T lymphocytes, B lymphocytes, macrophages,...

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Detalles Bibliográficos
Autores principales:	Santisteban-Espejo, Antonio, Bernal-Florindo, Irene, Perez-Requena, Jose, Atienza-Cuevas, Lidia, Maira-Gonzalez, Nieves, Garcia-Rojo, Marcial
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9631766/ https://www.ncbi.nlm.nih.gov/pubmed/36338756 http://dx.doi.org/10.3389/fonc.2022.1000762

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