Methyl Effect on the Metabolism, Chemical Stability, and Permeability Profile of Bioactive N-Sulfonylhydrazones

[Image: see text] Sulfonylhydrazones are privileged structures with multifaceted pharmacological activity. Exploring the hypoglycemic properties of these organic compounds, we previously revealed a new series of N-sulfonylhydrazones (NSH) as antidiabetic drug candidates. Here, we evaluated the micro...

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Detalles Bibliográficos
Autores principales: Guedes, Jéssica de Siqueira, Carneiro, Teiliane Rodrigues, Pinheiro, Pedro de Sena Murteira, Fraga, Carlos Alberto Manssour, Sant′Anna, Carlos Mauricio R., Barreiro, Eliezer J., Lima, Lídia Moreira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9631887/
https://www.ncbi.nlm.nih.gov/pubmed/36340078
http://dx.doi.org/10.1021/acsomega.2c04368

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9631887/
https://www.ncbi.nlm.nih.gov/pubmed/36340078
http://dx.doi.org/10.1021/acsomega.2c04368

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