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Iron Trichloride-Mediated Cascade Reaction of Aminosugar Derivatives for the Synthesis of Fused Tetrahydroisoquinoline–Tetrahydrofuran Systems

[Image: see text] A method to obtain tetrahydroisoquinolines (THIQs) fused to tetrahydrofuran rings from aminosugar derivatives has been developed. The procedure relies on a key deprotection of benzyl ethers followed by a double-cyclization sequence, using FeCl(3) as the sole reagent. This tandem re...

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Detalles Bibliográficos
Autores principales: Rodríguez-Álvarez, Sandra, Palazón, José M., Dorta, Rosa L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9631894/
https://www.ncbi.nlm.nih.gov/pubmed/36340113
http://dx.doi.org/10.1021/acsomega.2c04804