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The p-STAT3/ANXA2 axis promotes caspase-1-mediated hepatocyte pyroptosis in non-alcoholic steatohepatitis

BACKGROUND: To explore the roles of Annexin A2 (ANXA2) on hepatocyte pyroptosis and hepatic fibrosis in nonalcoholic steatohepatitis (NASH) and underlying molecular mechanism. METHODS: Bioinformatics analyses were performed on transcriptome data of liver tissues from mice and patients with liver fib...

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Detalles Bibliográficos
Autores principales:	Feng, Yun, Li, Wenhua, Wang, Zhuoya, Zhang, Ruling, Li, Yan, Zang, Lijuan, Wang, Peiwen, Li, Zhenghong, Dong, Yuwei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9632054/ https://www.ncbi.nlm.nih.gov/pubmed/36324154 http://dx.doi.org/10.1186/s12967-022-03692-1

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