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Biomedical named entity recognition with the combined feature attention and fully-shared multi-task learning

BACKGROUND: Biomedical named entity recognition (BioNER) is a basic and important task for biomedical text mining with the purpose of automatically recognizing and classifying biomedical entities. The performance of BioNER systems directly impacts downstream applications. Recently, deep neural netwo...

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Autores principales: Zhang, Zhiyu, Chen, Arbee L. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9632084/
https://www.ncbi.nlm.nih.gov/pubmed/36329384
http://dx.doi.org/10.1186/s12859-022-04994-3
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author Zhang, Zhiyu
Chen, Arbee L. P.
author_facet Zhang, Zhiyu
Chen, Arbee L. P.
author_sort Zhang, Zhiyu
collection PubMed
description BACKGROUND: Biomedical named entity recognition (BioNER) is a basic and important task for biomedical text mining with the purpose of automatically recognizing and classifying biomedical entities. The performance of BioNER systems directly impacts downstream applications. Recently, deep neural networks, especially pre-trained language models, have made great progress for BioNER. However, because of the lack of high-quality and large-scale annotated data and relevant external knowledge, the capability of the BioNER system remains limited. RESULTS: In this paper, we propose a novel fully-shared multi-task learning model based on the pre-trained language model in biomedical domain, namely BioBERT, with a new attention module to integrate the auto-processed syntactic information for the BioNER task. We have conducted numerous experiments on seven benchmark BioNER datasets. The proposed best multi-task model obtains F1 score improvements of 1.03% on BC2GM, 0.91% on NCBI-disease, 0.81% on Linnaeus, 1.26% on JNLPBA, 0.82% on BC5CDR-Chemical, 0.87% on BC5CDR-Disease, and 1.10% on Species-800 compared to the single-task BioBERT model. CONCLUSION: The results demonstrate our model outperforms previous studies on all datasets. Further analysis and case studies are also provided to prove the importance of the proposed attention module and fully-shared multi-task learning method used in our model.
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spelling pubmed-96320842022-11-04 Biomedical named entity recognition with the combined feature attention and fully-shared multi-task learning Zhang, Zhiyu Chen, Arbee L. P. BMC Bioinformatics Research BACKGROUND: Biomedical named entity recognition (BioNER) is a basic and important task for biomedical text mining with the purpose of automatically recognizing and classifying biomedical entities. The performance of BioNER systems directly impacts downstream applications. Recently, deep neural networks, especially pre-trained language models, have made great progress for BioNER. However, because of the lack of high-quality and large-scale annotated data and relevant external knowledge, the capability of the BioNER system remains limited. RESULTS: In this paper, we propose a novel fully-shared multi-task learning model based on the pre-trained language model in biomedical domain, namely BioBERT, with a new attention module to integrate the auto-processed syntactic information for the BioNER task. We have conducted numerous experiments on seven benchmark BioNER datasets. The proposed best multi-task model obtains F1 score improvements of 1.03% on BC2GM, 0.91% on NCBI-disease, 0.81% on Linnaeus, 1.26% on JNLPBA, 0.82% on BC5CDR-Chemical, 0.87% on BC5CDR-Disease, and 1.10% on Species-800 compared to the single-task BioBERT model. CONCLUSION: The results demonstrate our model outperforms previous studies on all datasets. Further analysis and case studies are also provided to prove the importance of the proposed attention module and fully-shared multi-task learning method used in our model. BioMed Central 2022-11-03 /pmc/articles/PMC9632084/ /pubmed/36329384 http://dx.doi.org/10.1186/s12859-022-04994-3 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Zhang, Zhiyu
Chen, Arbee L. P.
Biomedical named entity recognition with the combined feature attention and fully-shared multi-task learning
title Biomedical named entity recognition with the combined feature attention and fully-shared multi-task learning
title_full Biomedical named entity recognition with the combined feature attention and fully-shared multi-task learning
title_fullStr Biomedical named entity recognition with the combined feature attention and fully-shared multi-task learning
title_full_unstemmed Biomedical named entity recognition with the combined feature attention and fully-shared multi-task learning
title_short Biomedical named entity recognition with the combined feature attention and fully-shared multi-task learning
title_sort biomedical named entity recognition with the combined feature attention and fully-shared multi-task learning
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9632084/
https://www.ncbi.nlm.nih.gov/pubmed/36329384
http://dx.doi.org/10.1186/s12859-022-04994-3
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