Phosphodiesterase 10A (PDE10A) as a novel target to suppress β-catenin and RAS signaling in epithelial ovarian cancer

A leading theory for ovarian carcinogenesis proposes that inflammation associated with incessant ovulation is a driver of oncogenesis. Consistent with this theory, nonsteroidal anti-inflammatory drugs (NSAIDs) exert promising chemopreventive activity for ovarian cancer. Unfortunately, toxicity is as...

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Detalles Bibliográficos
Autores principales: Borneman, Rebecca M., Gavin, Elaine, Musiyenko, Alla, Richter, Wito, Lee, Kevin J., Crossman, David K., Andrews, Joel F., Wilhite, Annelise M., McClellan, Steven, Aragon, Ileana, Ward, Antonio B., Chen, Xi, Keeton, Adam B., Berry, Kristy, Piazza, Gary A., Scalici, Jennifer M., da Silva, Luciana Madeira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9632086/
https://www.ncbi.nlm.nih.gov/pubmed/36324187
http://dx.doi.org/10.1186/s13048-022-01050-9

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