IL7RA single nucleotide polymorphisms are associated with the size and function of the MAIT cell population in treated HIV-1 infection

MAIT cells are persistently depleted and functionally exhausted in HIV-1-infected patients despite long-term combination antiretroviral therapy (cART). IL-7 treatment supports MAIT cell reconstitution in vivo HIV-1-infected individuals and rescues their functionality in vitro. Single-nucleotide poly...

Descripción completa

Detalles Bibliográficos
Autores principales: Han, Fei, Gulam, Muhammad Yaaseen, Zheng, Yichao, Zulhaimi, Nurul Syuhada, Sia, Wan Rong, He, Dan, Ho, Amanda, Hadadi, Leila, Liu, Zhenyu, Qin, Peiwu, Lobie, Peter E., Kamarulzaman, Adeeba, Wang, Lin-Fa, Sandberg, Johan K., Lewin, Sharon R., Rajasuriar, Reena, Leeansyah, Edwin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9632172/
https://www.ncbi.nlm.nih.gov/pubmed/36341446
http://dx.doi.org/10.3389/fimmu.2022.985385

Ejemplares similares

Ejemplares similares