Low serological rate of SARS-CoV-2 in cats from military bases in Israel

Domestic cats are susceptible to SARS-CoV-2 infection and can transmit the virus to other felines. A high number of COVID-19 human cases within the military personnel and a high density of stray cats living close to soldiers raised the need to perform active animal surveillance. We validated a novel...

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Autores principales: Kleinerman, Gabriela, Gross, Saar, Topol, Shira, Ariel, Ella, Volokh, Gerry, Melloul, Sivan, Mergy, Shani Etty, Malamud, Yaakov, Gilboa, Sagi, Gal, Yoav, Weiss, Libby, Richt, Juergen A., Decaro, Nicola, Eskandar, Shadi, Arieli, Yarden, Gingis, Efrat, Sachter, Yacov, Chaim, Lavie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9632235/
https://www.ncbi.nlm.nih.gov/pubmed/36356507
http://dx.doi.org/10.1016/j.cimid.2022.101905
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author Kleinerman, Gabriela
Gross, Saar
Topol, Shira
Ariel, Ella
Volokh, Gerry
Melloul, Sivan
Mergy, Shani Etty
Malamud, Yaakov
Gilboa, Sagi
Gal, Yoav
Weiss, Libby
Richt, Juergen A.
Decaro, Nicola
Eskandar, Shadi
Arieli, Yarden
Gingis, Efrat
Sachter, Yacov
Chaim, Lavie
author_facet Kleinerman, Gabriela
Gross, Saar
Topol, Shira
Ariel, Ella
Volokh, Gerry
Melloul, Sivan
Mergy, Shani Etty
Malamud, Yaakov
Gilboa, Sagi
Gal, Yoav
Weiss, Libby
Richt, Juergen A.
Decaro, Nicola
Eskandar, Shadi
Arieli, Yarden
Gingis, Efrat
Sachter, Yacov
Chaim, Lavie
author_sort Kleinerman, Gabriela
collection PubMed
description Domestic cats are susceptible to SARS-CoV-2 infection and can transmit the virus to other felines. A high number of COVID-19 human cases within the military personnel and a high density of stray cats living close to soldiers raised the need to perform active animal surveillance. We validated a novel quantitative serological microarray for use in cats, that enables simultaneous detection of IgG and IgM responses; in addition, molecular genetic SARS-CoV-2 detection was performed. Three out of 131 cats analyzed, showed IgG antibodies against SARS-CoV-2 RBD and S2P (2.3 %). None of cats were positive for SARS-CoV-2 RNA by RT-PCR. SARS-CoV-2 infection rate in soldiers ranged from 4.7 % to 16 % (average rate=8.9 %). Further investigations on a larger cohort are necessary, in the light of the emerging new viral variants in other animal species and in humans.
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spelling pubmed-96322352022-11-03 Low serological rate of SARS-CoV-2 in cats from military bases in Israel Kleinerman, Gabriela Gross, Saar Topol, Shira Ariel, Ella Volokh, Gerry Melloul, Sivan Mergy, Shani Etty Malamud, Yaakov Gilboa, Sagi Gal, Yoav Weiss, Libby Richt, Juergen A. Decaro, Nicola Eskandar, Shadi Arieli, Yarden Gingis, Efrat Sachter, Yacov Chaim, Lavie Comp Immunol Microbiol Infect Dis Article Domestic cats are susceptible to SARS-CoV-2 infection and can transmit the virus to other felines. A high number of COVID-19 human cases within the military personnel and a high density of stray cats living close to soldiers raised the need to perform active animal surveillance. We validated a novel quantitative serological microarray for use in cats, that enables simultaneous detection of IgG and IgM responses; in addition, molecular genetic SARS-CoV-2 detection was performed. Three out of 131 cats analyzed, showed IgG antibodies against SARS-CoV-2 RBD and S2P (2.3 %). None of cats were positive for SARS-CoV-2 RNA by RT-PCR. SARS-CoV-2 infection rate in soldiers ranged from 4.7 % to 16 % (average rate=8.9 %). Further investigations on a larger cohort are necessary, in the light of the emerging new viral variants in other animal species and in humans. Elsevier Ltd. 2022 2022-11-03 /pmc/articles/PMC9632235/ /pubmed/36356507 http://dx.doi.org/10.1016/j.cimid.2022.101905 Text en © 2022 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Kleinerman, Gabriela
Gross, Saar
Topol, Shira
Ariel, Ella
Volokh, Gerry
Melloul, Sivan
Mergy, Shani Etty
Malamud, Yaakov
Gilboa, Sagi
Gal, Yoav
Weiss, Libby
Richt, Juergen A.
Decaro, Nicola
Eskandar, Shadi
Arieli, Yarden
Gingis, Efrat
Sachter, Yacov
Chaim, Lavie
Low serological rate of SARS-CoV-2 in cats from military bases in Israel
title Low serological rate of SARS-CoV-2 in cats from military bases in Israel
title_full Low serological rate of SARS-CoV-2 in cats from military bases in Israel
title_fullStr Low serological rate of SARS-CoV-2 in cats from military bases in Israel
title_full_unstemmed Low serological rate of SARS-CoV-2 in cats from military bases in Israel
title_short Low serological rate of SARS-CoV-2 in cats from military bases in Israel
title_sort low serological rate of sars-cov-2 in cats from military bases in israel
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9632235/
https://www.ncbi.nlm.nih.gov/pubmed/36356507
http://dx.doi.org/10.1016/j.cimid.2022.101905
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