Structure and inhibition of SARS-CoV-1 and SARS-CoV-2 main proteases by oral antiviral compound AG7404

Severe acute respiratory syndrome coronaviruses 1 and 2 (SARS-CoV-1 and SARS-CoV-2) pose a threat to global public health. The 3C-like main protease (M(pro)), which presents structural similarity with the active site domain of enterovirus 3C protease, is one of the best-characterized drug targets of...

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Detalles Bibliográficos
Autores principales: Fàbrega-Ferrer, Montserrat, Herrera-Morandé, Alejandra, Muriel-Goñi, Sara, Pérez-Saavedra, Julia, Bueno, Paula, Castro, Victoria, Garaigorta, Urtzi, Gastaminza, Pablo, Coll, Miquel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier B.V. 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9632241/
https://www.ncbi.nlm.nih.gov/pubmed/36336176
http://dx.doi.org/10.1016/j.antiviral.2022.105458

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