TP53 Alterations Are Associated With Poor Survival in Patients With Primary Mediastinal Nonseminoma Germ Cell Tumors

BACKGROUND: Primary mediastinal nonseminoma germ cell tumors (PMNSGCT) are a subgroup of nonseminoma germ cell tumors (GCT) with poor prognosis. In this study, PMNSGCT-specific genomic landscape was analyzed and correlated with clinical outcomes. METHODS: DNA was extracted and sequenced from 28 arch...

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Detalles Bibliográficos
Autores principales: Bacon, Jack V W, Giannatempo, Patrizia, Cataldo, Giovanna, Fazli, Ladan, Saxena, Neetu, Ozgun, Guliz, Soleimani, Maryam, Chi, Kim, Nichols, Craig, Necchi, Andrea, Wyatt, Alexander W, Kollmannsberger, Christian K, Nappi, Lucia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9632310/
https://www.ncbi.nlm.nih.gov/pubmed/36166584
http://dx.doi.org/10.1093/oncolo/oyac197

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