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aPKC regulates apical constriction to prevent tissue rupture in the Drosophila follicular epithelium

Apical-basal polarity is an essential epithelial trait controlled by the evolutionarily conserved PAR-aPKC polarity network. Dysregulation of polarity proteins disrupts tissue organization during development and in disease, but the underlying mechanisms are unclear due to the broad implications of p...

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Detalles Bibliográficos
Autores principales: Osswald, Mariana, Barros-Carvalho, André, Carmo, Ana M., Loyer, Nicolas, Gracio, Patricia C., Sunkel, Claudio E., Homem, Catarina C.F., Januschke, Jens, Morais-de-Sá, Eurico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9632327/
https://www.ncbi.nlm.nih.gov/pubmed/36113470
http://dx.doi.org/10.1016/j.cub.2022.08.063

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