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aPKC regulates apical constriction to prevent tissue rupture in the Drosophila follicular epithelium
Apical-basal polarity is an essential epithelial trait controlled by the evolutionarily conserved PAR-aPKC polarity network. Dysregulation of polarity proteins disrupts tissue organization during development and in disease, but the underlying mechanisms are unclear due to the broad implications of p...
Autores principales: | Osswald, Mariana, Barros-Carvalho, André, Carmo, Ana M., Loyer, Nicolas, Gracio, Patricia C., Sunkel, Claudio E., Homem, Catarina C.F., Januschke, Jens, Morais-de-Sá, Eurico |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9632327/ https://www.ncbi.nlm.nih.gov/pubmed/36113470 http://dx.doi.org/10.1016/j.cub.2022.08.063 |
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