Lack of evidence of viability and infectivity of SARS-CoV-2 in the fecal specimens of COVID-19 patients

SARS-CoV-2 can be shed in feces and can enter sewage systems. In order to implement effective control measures and identify new channels of transmission, it is essential to identify the presence of infectious virus particles in feces and sewage. In this study, we attempt to utilize Molecular techniq...

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Detalles Bibliográficos
Autores principales: Joshi, Madhuri, Mohandas, Sreelekshmy, Prasad, Sharda, Shinde, Manohar, Chavan, Nutan, Yadav, Pragya D., Lavania, Mallika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Public Health
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9632423/
https://www.ncbi.nlm.nih.gov/pubmed/36339137
http://dx.doi.org/10.3389/fpubh.2022.1030249
Descripción
Sumario:SARS-CoV-2 can be shed in feces and can enter sewage systems. In order to implement effective control measures and identify new channels of transmission, it is essential to identify the presence of infectious virus particles in feces and sewage. In this study, we attempt to utilize Molecular techniques, cell cultures and animal models to find out the infectivity of SARS-CoV-2 in the feces of COVID-19 patients. Our findings exclude the presence of infectious virus particles, suggesting that fecal-oral transmission may not be the main mode of transmission. Larger-scale initiatives are nevertheless required, particularly considering the emergence of new viral strains.

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