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Lack of evidence of viability and infectivity of SARS-CoV-2 in the fecal specimens of COVID-19 patients
SARS-CoV-2 can be shed in feces and can enter sewage systems. In order to implement effective control measures and identify new channels of transmission, it is essential to identify the presence of infectious virus particles in feces and sewage. In this study, we attempt to utilize Molecular techniq...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9632423/ https://www.ncbi.nlm.nih.gov/pubmed/36339137 http://dx.doi.org/10.3389/fpubh.2022.1030249 |
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author | Joshi, Madhuri Mohandas, Sreelekshmy Prasad, Sharda Shinde, Manohar Chavan, Nutan Yadav, Pragya D. Lavania, Mallika |
author_facet | Joshi, Madhuri Mohandas, Sreelekshmy Prasad, Sharda Shinde, Manohar Chavan, Nutan Yadav, Pragya D. Lavania, Mallika |
author_sort | Joshi, Madhuri |
collection | PubMed |
description | SARS-CoV-2 can be shed in feces and can enter sewage systems. In order to implement effective control measures and identify new channels of transmission, it is essential to identify the presence of infectious virus particles in feces and sewage. In this study, we attempt to utilize Molecular techniques, cell cultures and animal models to find out the infectivity of SARS-CoV-2 in the feces of COVID-19 patients. Our findings exclude the presence of infectious virus particles, suggesting that fecal-oral transmission may not be the main mode of transmission. Larger-scale initiatives are nevertheless required, particularly considering the emergence of new viral strains. |
format | Online Article Text |
id | pubmed-9632423 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-96324232022-11-04 Lack of evidence of viability and infectivity of SARS-CoV-2 in the fecal specimens of COVID-19 patients Joshi, Madhuri Mohandas, Sreelekshmy Prasad, Sharda Shinde, Manohar Chavan, Nutan Yadav, Pragya D. Lavania, Mallika Front Public Health Public Health SARS-CoV-2 can be shed in feces and can enter sewage systems. In order to implement effective control measures and identify new channels of transmission, it is essential to identify the presence of infectious virus particles in feces and sewage. In this study, we attempt to utilize Molecular techniques, cell cultures and animal models to find out the infectivity of SARS-CoV-2 in the feces of COVID-19 patients. Our findings exclude the presence of infectious virus particles, suggesting that fecal-oral transmission may not be the main mode of transmission. Larger-scale initiatives are nevertheless required, particularly considering the emergence of new viral strains. Frontiers Media S.A. 2022-10-20 /pmc/articles/PMC9632423/ /pubmed/36339137 http://dx.doi.org/10.3389/fpubh.2022.1030249 Text en Copyright © 2022 Joshi, Mohandas, Prasad, Shinde, Chavan, Yadav and Lavania. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Public Health Joshi, Madhuri Mohandas, Sreelekshmy Prasad, Sharda Shinde, Manohar Chavan, Nutan Yadav, Pragya D. Lavania, Mallika Lack of evidence of viability and infectivity of SARS-CoV-2 in the fecal specimens of COVID-19 patients |
title | Lack of evidence of viability and infectivity of SARS-CoV-2 in the fecal specimens of COVID-19 patients |
title_full | Lack of evidence of viability and infectivity of SARS-CoV-2 in the fecal specimens of COVID-19 patients |
title_fullStr | Lack of evidence of viability and infectivity of SARS-CoV-2 in the fecal specimens of COVID-19 patients |
title_full_unstemmed | Lack of evidence of viability and infectivity of SARS-CoV-2 in the fecal specimens of COVID-19 patients |
title_short | Lack of evidence of viability and infectivity of SARS-CoV-2 in the fecal specimens of COVID-19 patients |
title_sort | lack of evidence of viability and infectivity of sars-cov-2 in the fecal specimens of covid-19 patients |
topic | Public Health |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9632423/ https://www.ncbi.nlm.nih.gov/pubmed/36339137 http://dx.doi.org/10.3389/fpubh.2022.1030249 |
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