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Tyrosine phosphorylation regulates RIPK1 activity to limit cell death and inflammation

Receptor-interacting serine/threonine-protein kinase 1 (RIPK1) is a cytosolic protein kinase that regulates multiple inflammatory and cell death pathways. Serine/Threonine phosphorylation of RIPK1 is known to suppress RIPK1 kinase-mediated cell death in the contexts of inflammation, infection and em...

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Detalles Bibliográficos
Autores principales: Tu, Hailin, Xiong, Weihang, Zhang, Jie, Zhao, Xueqiang, Lin, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9632600/
https://www.ncbi.nlm.nih.gov/pubmed/36329033
http://dx.doi.org/10.1038/s41467-022-34080-4