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A global review of racial, ethnic and socio-economic disparities in multisystem inflammatory syndrome in children related to COVID-19

With over 500 million confirmed cases and 6.2 million deaths worldwide, the novel coronavirus has highlighted the underlying disparities in healthcare, unpreparedness to deal with a new disease and the need for monitoring and surveillance for a post-infectious syndrome as well as complicated disease...

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Autores principales: Asghar, Zoha, Sharaf, Kanza, Butt, Faran Ahmed, Shaikh, Omer Ahmed, Shekha, Manahil, Waris, Abdul, Ullah, Irfan, Nashwan, Abdulqadir J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9632619/
https://www.ncbi.nlm.nih.gov/pubmed/36339223
http://dx.doi.org/10.3389/fpubh.2022.996311
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author Asghar, Zoha
Sharaf, Kanza
Butt, Faran Ahmed
Shaikh, Omer Ahmed
Shekha, Manahil
Waris, Abdul
Ullah, Irfan
Nashwan, Abdulqadir J.
author_facet Asghar, Zoha
Sharaf, Kanza
Butt, Faran Ahmed
Shaikh, Omer Ahmed
Shekha, Manahil
Waris, Abdul
Ullah, Irfan
Nashwan, Abdulqadir J.
author_sort Asghar, Zoha
collection PubMed
description With over 500 million confirmed cases and 6.2 million deaths worldwide, the novel coronavirus has highlighted the underlying disparities in healthcare, unpreparedness to deal with a new disease and the need for monitoring and surveillance for a post-infectious syndrome as well as complicated diseases. Initially, children were thought to be spared but reports of a new phenomenon manifesting as Kawasaki-like disease, toxic shock syndrome, and multi-system inflammatory syndrome, which developed after a few weeks of severe COVID-19 infection, emerged in the pediatric population. As the pandemic progressed, increased prevalence of multi-system inflammatory syndrome in children (MIS-C) related to COVID-19 was seen in non-Hispanic blacks, Asians, and Latinos as compared to the white population drawing attention to a possible role of ethnicity and socio-economic disparities. The CDC currently reports that 31% of MIS-C cases were seen in Black Non-Hispanics and 26% in Latinos, who were historically more affected in previous pandemics. Furthermore, MIS-C cases in developing countries showed higher mortality as compared to high-income countries, which points toward the role of social determinants of health and limitations in a low-resource set up in increasing the disease burden of MIS-C, which should be treated as a public health emergency. Our review highlights the role of ethnicity, socio-economic factors, comorbidities, and differences in populations affected by MIS-C in high-income vs. low- and middle-income countries.
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spelling pubmed-96326192022-11-04 A global review of racial, ethnic and socio-economic disparities in multisystem inflammatory syndrome in children related to COVID-19 Asghar, Zoha Sharaf, Kanza Butt, Faran Ahmed Shaikh, Omer Ahmed Shekha, Manahil Waris, Abdul Ullah, Irfan Nashwan, Abdulqadir J. Front Public Health Public Health With over 500 million confirmed cases and 6.2 million deaths worldwide, the novel coronavirus has highlighted the underlying disparities in healthcare, unpreparedness to deal with a new disease and the need for monitoring and surveillance for a post-infectious syndrome as well as complicated diseases. Initially, children were thought to be spared but reports of a new phenomenon manifesting as Kawasaki-like disease, toxic shock syndrome, and multi-system inflammatory syndrome, which developed after a few weeks of severe COVID-19 infection, emerged in the pediatric population. As the pandemic progressed, increased prevalence of multi-system inflammatory syndrome in children (MIS-C) related to COVID-19 was seen in non-Hispanic blacks, Asians, and Latinos as compared to the white population drawing attention to a possible role of ethnicity and socio-economic disparities. The CDC currently reports that 31% of MIS-C cases were seen in Black Non-Hispanics and 26% in Latinos, who were historically more affected in previous pandemics. Furthermore, MIS-C cases in developing countries showed higher mortality as compared to high-income countries, which points toward the role of social determinants of health and limitations in a low-resource set up in increasing the disease burden of MIS-C, which should be treated as a public health emergency. Our review highlights the role of ethnicity, socio-economic factors, comorbidities, and differences in populations affected by MIS-C in high-income vs. low- and middle-income countries. Frontiers Media S.A. 2022-10-20 /pmc/articles/PMC9632619/ /pubmed/36339223 http://dx.doi.org/10.3389/fpubh.2022.996311 Text en Copyright © 2022 Asghar, Sharaf, Butt, Shaikh, Shekha, Waris, Ullah and Nashwan. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Public Health
Asghar, Zoha
Sharaf, Kanza
Butt, Faran Ahmed
Shaikh, Omer Ahmed
Shekha, Manahil
Waris, Abdul
Ullah, Irfan
Nashwan, Abdulqadir J.
A global review of racial, ethnic and socio-economic disparities in multisystem inflammatory syndrome in children related to COVID-19
title A global review of racial, ethnic and socio-economic disparities in multisystem inflammatory syndrome in children related to COVID-19
title_full A global review of racial, ethnic and socio-economic disparities in multisystem inflammatory syndrome in children related to COVID-19
title_fullStr A global review of racial, ethnic and socio-economic disparities in multisystem inflammatory syndrome in children related to COVID-19
title_full_unstemmed A global review of racial, ethnic and socio-economic disparities in multisystem inflammatory syndrome in children related to COVID-19
title_short A global review of racial, ethnic and socio-economic disparities in multisystem inflammatory syndrome in children related to COVID-19
title_sort global review of racial, ethnic and socio-economic disparities in multisystem inflammatory syndrome in children related to covid-19
topic Public Health
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9632619/
https://www.ncbi.nlm.nih.gov/pubmed/36339223
http://dx.doi.org/10.3389/fpubh.2022.996311
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