Effects of amikacin, polymyxin-B, and sulbactam combination on the pharmacodynamic indices of mutant selection against multi-drug resistant Acinetobacter baumannii

Amikacin and polymyxins as monotherapies are ineffective against multidrug-resistant Acinetobacter baumannii at the clinical dose. When polymyxins, aminoglycosides, and sulbactam are co-administered, the combinations exhibit in vitro synergistic activities. The minimum inhibitory concentration (MIC)...

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Detalles Bibliográficos
Autores principales: Zhu, Shixing, Song, Chu, Zhang, Jiayuan, Diao, Shuo, Heinrichs, Tobias M., Martins, Frederico S., Lv, Zhihua, Zhu, Yuanqi, Yu, Mingming, Sy, Sherwin K. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9632654/
https://www.ncbi.nlm.nih.gov/pubmed/36338049
http://dx.doi.org/10.3389/fmicb.2022.1013939

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9632654/
https://www.ncbi.nlm.nih.gov/pubmed/36338049
http://dx.doi.org/10.3389/fmicb.2022.1013939

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