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Modulation of NMDA receptor activity by CR4056, an imidazoline-2 receptor ligand with analgesic properties

CR4056 is an imidazoline-2 receptor ligand having potent analgesic activity and synergistic effect with opioids. Very recently it has been found that CR4056 can revert the cognitive impairment in animal models of Alzheimer's disease (AD). Since several lines of evidence highlight the importance...

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Detalles Bibliográficos
Autores principales: Puja, Giulia, Losi, Gabriele, Rovati, Lucio, Lanza, Marco, Caselli, Gianfranco, Bardoni, Rita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9632859/
https://www.ncbi.nlm.nih.gov/pubmed/36341153
http://dx.doi.org/10.3389/fpain.2022.1003068

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