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Modulation of NMDA receptor activity by CR4056, an imidazoline-2 receptor ligand with analgesic properties
CR4056 is an imidazoline-2 receptor ligand having potent analgesic activity and synergistic effect with opioids. Very recently it has been found that CR4056 can revert the cognitive impairment in animal models of Alzheimer's disease (AD). Since several lines of evidence highlight the importance...
Autores principales: | Puja, Giulia, Losi, Gabriele, Rovati, Lucio, Lanza, Marco, Caselli, Gianfranco, Bardoni, Rita |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9632859/ https://www.ncbi.nlm.nih.gov/pubmed/36341153 http://dx.doi.org/10.3389/fpain.2022.1003068 |
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