Leonurine inhibits cardiomyocyte pyroptosis to attenuate cardiac fibrosis via the TGF-β/Smad2 signalling pathway

Cardiac fibrosis is a common cause of most cardiovascular diseases. Leonurine, an alkaloid from Herba leonuri, had been indicated to treat cardiovascular diseases due to its cardioprotective effects. Recently, pyroptosis, a programmed form of cell death that releases inflammatory factors, has been s...

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Detalles Bibliográficos
Autores principales: Li, Zhaoyi, Chen, Keyuan, Zhu, Yi Zhun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9632889/
https://www.ncbi.nlm.nih.gov/pubmed/36327230
http://dx.doi.org/10.1371/journal.pone.0275258

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9632889/
https://www.ncbi.nlm.nih.gov/pubmed/36327230
http://dx.doi.org/10.1371/journal.pone.0275258

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