Prurigo Nodularis Eruption Triggered by SARS-CoV-2 Vaccine

We discuss a case of a 63-year-old male who presented with generalized itchy papulonodular rash a few weeks after receiving a vaccination against SARS-CoV-2. The patient had a negative medical history for atopic dermatitis and other pruritic skin conditions, and clinical presentation was consistent...

Descripción completa

Detalles Bibliográficos
Autores principales: Barnawi, Ghassan, Alghamdi, Fareeda S, Almuqati, Amer S, Alamri, Awadh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Dermatology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9633006/
https://www.ncbi.nlm.nih.gov/pubmed/36348898
http://dx.doi.org/10.7759/cureus.29914
_version_ 1784824167546224640
author Barnawi, Ghassan
Alghamdi, Fareeda S
Almuqati, Amer S
Alamri, Awadh
author_facet Barnawi, Ghassan
Alghamdi, Fareeda S
Almuqati, Amer S
Alamri, Awadh
author_sort Barnawi, Ghassan
collection PubMed
description We discuss a case of a 63-year-old male who presented with generalized itchy papulonodular rash a few weeks after receiving a vaccination against SARS-CoV-2. The patient had a negative medical history for atopic dermatitis and other pruritic skin conditions, and clinical presentation was consistent with prurigo nodularis, which was confirmed later by tissue biopsy and microscopic analysis. The pathophysiology of this skin condition is thought to be due to an overlap between the immune and nervous systems. Due to the hypothesized involvement of the immune system in this disease, it. is presumed that the patient had a dysregulated immune response caused by his recent SARS-CoV-2 vaccination. 
format Online
Article
Text
id pubmed-9633006
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Cureus
record_format MEDLINE/PubMed
spelling pubmed-96330062022-11-07 Prurigo Nodularis Eruption Triggered by SARS-CoV-2 Vaccine Barnawi, Ghassan Alghamdi, Fareeda S Almuqati, Amer S Alamri, Awadh Cureus Dermatology We discuss a case of a 63-year-old male who presented with generalized itchy papulonodular rash a few weeks after receiving a vaccination against SARS-CoV-2. The patient had a negative medical history for atopic dermatitis and other pruritic skin conditions, and clinical presentation was consistent with prurigo nodularis, which was confirmed later by tissue biopsy and microscopic analysis. The pathophysiology of this skin condition is thought to be due to an overlap between the immune and nervous systems. Due to the hypothesized involvement of the immune system in this disease, it. is presumed that the patient had a dysregulated immune response caused by his recent SARS-CoV-2 vaccination.  Cureus 2022-10-04 /pmc/articles/PMC9633006/ /pubmed/36348898 http://dx.doi.org/10.7759/cureus.29914 Text en Copyright © 2022, Barnawi et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Dermatology
Barnawi, Ghassan
Alghamdi, Fareeda S
Almuqati, Amer S
Alamri, Awadh
Prurigo Nodularis Eruption Triggered by SARS-CoV-2 Vaccine
title Prurigo Nodularis Eruption Triggered by SARS-CoV-2 Vaccine
title_full Prurigo Nodularis Eruption Triggered by SARS-CoV-2 Vaccine
title_fullStr Prurigo Nodularis Eruption Triggered by SARS-CoV-2 Vaccine
title_full_unstemmed Prurigo Nodularis Eruption Triggered by SARS-CoV-2 Vaccine
title_short Prurigo Nodularis Eruption Triggered by SARS-CoV-2 Vaccine
title_sort prurigo nodularis eruption triggered by sars-cov-2 vaccine
topic Dermatology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9633006/
https://www.ncbi.nlm.nih.gov/pubmed/36348898
http://dx.doi.org/10.7759/cureus.29914
work_keys_str_mv AT barnawighassan prurigonodulariseruptiontriggeredbysarscov2vaccine
AT alghamdifareedas prurigonodulariseruptiontriggeredbysarscov2vaccine
AT almuqatiamers prurigonodulariseruptiontriggeredbysarscov2vaccine
AT alamriawadh prurigonodulariseruptiontriggeredbysarscov2vaccine

Ejemplares similares