Cargando…

Rates of Future Lumbar Fusion in Patients with Cauda Equina Syndrome Treated With Decompression

The long-term risk of conversion to lumbar fusion is ill-defined for patients with cauda equina syndrome (CES) treated with decompression. This study aimed to identify the rates of fusion in patients with CES and compare those rates with a matched lumbar spinal stenosis (LSS) group. METHODS: Patient...

Descripción completa

Detalles Bibliográficos
Autores principales: Seidel, Henry D., Pirkle, Sean, Bhattacharjee, Sarah, Baker, Hayden P., Lee, Michael J., El Dafrawy, Mostafa H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9633085/
https://www.ncbi.nlm.nih.gov/pubmed/36322672
http://dx.doi.org/10.5435/JAAOSGlobal-D-22-00153
_version_ 1784824186574733312
author Seidel, Henry D.
Pirkle, Sean
Bhattacharjee, Sarah
Baker, Hayden P.
Lee, Michael J.
El Dafrawy, Mostafa H.
author_facet Seidel, Henry D.
Pirkle, Sean
Bhattacharjee, Sarah
Baker, Hayden P.
Lee, Michael J.
El Dafrawy, Mostafa H.
author_sort Seidel, Henry D.
collection PubMed
description The long-term risk of conversion to lumbar fusion is ill-defined for patients with cauda equina syndrome (CES) treated with decompression. This study aimed to identify the rates of fusion in patients with CES and compare those rates with a matched lumbar spinal stenosis (LSS) group. METHODS: Patients with CES who underwent decompression were identified in a national database and matched to control patients with LSS. The rates of conversion to fusion were identified and compared. Multivariate logistic regression analysis identified independently associated risk factors. A subanalysis was conducted after stratifying by timing between CES diagnosis and decompression. RESULTS: The rate of lumbar fusion in the CES cohort was 3.6% after 1 year, 6.7% after 3 years, and 7.8% after 5 years, significantly higher than the LSS control group at all time points (1 year: 1.6%, P = 0.001; 3 years: 3.0%, P < 0.001; 5 years: 3.8%, P < 0.001). CES was independently associated with increased risk of conversion to fusion (odds ratio: 2.13; 95% confidence interval: 1.56 to 2.97; P < 0.001). Surgical timing was not associated with risk of conversion to fusion. CONCLUSIONS: After 5 years, 7.8% of patients with CES underwent fusion, a markedly higher rate compared with patients with LSS. Counseling patients with CES on this increased risk of future surgery is important for patient education and satisfaction.
format Online
Article
Text
id pubmed-9633085
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Wolters Kluwer
record_format MEDLINE/PubMed
spelling pubmed-96330852022-11-07 Rates of Future Lumbar Fusion in Patients with Cauda Equina Syndrome Treated With Decompression Seidel, Henry D. Pirkle, Sean Bhattacharjee, Sarah Baker, Hayden P. Lee, Michael J. El Dafrawy, Mostafa H. J Am Acad Orthop Surg Glob Res Rev Research Article The long-term risk of conversion to lumbar fusion is ill-defined for patients with cauda equina syndrome (CES) treated with decompression. This study aimed to identify the rates of fusion in patients with CES and compare those rates with a matched lumbar spinal stenosis (LSS) group. METHODS: Patients with CES who underwent decompression were identified in a national database and matched to control patients with LSS. The rates of conversion to fusion were identified and compared. Multivariate logistic regression analysis identified independently associated risk factors. A subanalysis was conducted after stratifying by timing between CES diagnosis and decompression. RESULTS: The rate of lumbar fusion in the CES cohort was 3.6% after 1 year, 6.7% after 3 years, and 7.8% after 5 years, significantly higher than the LSS control group at all time points (1 year: 1.6%, P = 0.001; 3 years: 3.0%, P < 0.001; 5 years: 3.8%, P < 0.001). CES was independently associated with increased risk of conversion to fusion (odds ratio: 2.13; 95% confidence interval: 1.56 to 2.97; P < 0.001). Surgical timing was not associated with risk of conversion to fusion. CONCLUSIONS: After 5 years, 7.8% of patients with CES underwent fusion, a markedly higher rate compared with patients with LSS. Counseling patients with CES on this increased risk of future surgery is important for patient education and satisfaction. Wolters Kluwer 2022-11-02 /pmc/articles/PMC9633085/ /pubmed/36322672 http://dx.doi.org/10.5435/JAAOSGlobal-D-22-00153 Text en Copyright © 2022 The Authors. Published by Wolters Kluwer Health, Inc. on behalf of the American Academy of Orthopaedic Surgeons. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY) (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Seidel, Henry D.
Pirkle, Sean
Bhattacharjee, Sarah
Baker, Hayden P.
Lee, Michael J.
El Dafrawy, Mostafa H.
Rates of Future Lumbar Fusion in Patients with Cauda Equina Syndrome Treated With Decompression
title Rates of Future Lumbar Fusion in Patients with Cauda Equina Syndrome Treated With Decompression
title_full Rates of Future Lumbar Fusion in Patients with Cauda Equina Syndrome Treated With Decompression
title_fullStr Rates of Future Lumbar Fusion in Patients with Cauda Equina Syndrome Treated With Decompression
title_full_unstemmed Rates of Future Lumbar Fusion in Patients with Cauda Equina Syndrome Treated With Decompression
title_short Rates of Future Lumbar Fusion in Patients with Cauda Equina Syndrome Treated With Decompression
title_sort rates of future lumbar fusion in patients with cauda equina syndrome treated with decompression
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9633085/
https://www.ncbi.nlm.nih.gov/pubmed/36322672
http://dx.doi.org/10.5435/JAAOSGlobal-D-22-00153
work_keys_str_mv AT seidelhenryd ratesoffuturelumbarfusioninpatientswithcaudaequinasyndrometreatedwithdecompression
AT pirklesean ratesoffuturelumbarfusioninpatientswithcaudaequinasyndrometreatedwithdecompression
AT bhattacharjeesarah ratesoffuturelumbarfusioninpatientswithcaudaequinasyndrometreatedwithdecompression
AT bakerhaydenp ratesoffuturelumbarfusioninpatientswithcaudaequinasyndrometreatedwithdecompression
AT leemichaelj ratesoffuturelumbarfusioninpatientswithcaudaequinasyndrometreatedwithdecompression
AT eldafrawymostafah ratesoffuturelumbarfusioninpatientswithcaudaequinasyndrometreatedwithdecompression