Efficacy of mucosal vaccination using a protozoan parasite as a vehicle for antigen delivery: IgG and neutralizing response after rectal administration of LeCoVax-2, a candidate vaccine against COVID-19

Mucosal vaccination is regarded as a promising alternative to classical, intramuscular vaccine delivery. However, only a limited number of vaccines have been licensed for mucosal administration in humans. Here we propose Leishmania tarentolae, a protozoan parasite, as a potential antigen vehicle for...

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Detalles Bibliográficos
Autores principales: Epis, Sara, Varotto-Boccazzi, Ilaria, Manenti, Alessandro, Rubolini, Diego, Gabrieli, Paolo, Cattaneo, Giulia Maria, Gourlay, Louise, Dapporto, Francesca, Monti, Martina, Razzano, Ilaria, Leonardi, Margherita, Iannacone, Matteo, Recordati, Camilla, Bertola, Luca, Fiorina, Paolo, Marvasi, Luigi, Montomoli, Emanuele, Zuccotti, Gianvincenzo, Bandi, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier Ltd. 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9633108/
https://www.ncbi.nlm.nih.gov/pubmed/36336215
http://dx.doi.org/10.1016/j.phrs.2022.106546

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