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m6A Methyltransferase METTL3 Reduces Hippocampal Neuron Apoptosis in a Mouse Model of Autism Through the MALAT1/SFRP2/Wnt/β-catenin Axis

OBJECTIVE: Hippocampal neuron apoptosis contributes to autism, while METTL3 has been documented to possess great potentials in neuron apoptosis. Our study probed into the role of METTL3 in neuron apoptosis in autism and to determine the underlying mechanism. METHODS: Bioinformatics analysis was used...

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Detalles Bibliográficos
Autores principales:	Ming, Yue, Deng, Zhihui, Tian, Xianhua, Jia, Yuerong, Ning, Meng, Cheng, Shuhua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Neuropsychiatric Association 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9633173/ https://www.ncbi.nlm.nih.gov/pubmed/36327957 http://dx.doi.org/10.30773/pi.2021.0370

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