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Development of QSAR models to predict blood-brain barrier permeability

Assessing drug permeability across the blood-brain barrier (BBB) is important when evaluating the abuse potential of new pharmaceuticals as well as developing novel therapeutics that target central nervous system disorders. One of the gold-standard in vivo methods for determining BBB permeability is...

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Detalles Bibliográficos
Autores principales: Faramarzi, Sadegh, Kim, Marlene T., Volpe, Donna A., Cross, Kevin P., Chakravarti, Suman, Stavitskaya, Lidiya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9633177/
https://www.ncbi.nlm.nih.gov/pubmed/36339562
http://dx.doi.org/10.3389/fphar.2022.1040838