Apelin‐mediated deamidation of HMGA1 promotes tumorigenesis by enhancing SREBP1 activity and lipid synthesis

Enhanced fatty acid synthesis provides proliferation and survival advantages for tumor cells. Apelin is an adipokine, which serves as a ligand of G protein–coupled receptors that promote tumor growth in malignant cancers. Here, we confirmed that apelin increased sterol regulatory element–binding pro...

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Detalles Bibliográficos
Autores principales: Zhu, Yihan, Yang, Ying, Bu, Hong, Huang, Hong, Chen, Hongyu, Ran, Jingjing, Qin, Liwen, Ni, Yinyun, Yao, Menglin, Song, Tingting, Li, Mufeng, Yang, Yongfeng, Guo, Tingting, Chao, Ningning, Liu, Zhiqing, Li, Weimin, Zhang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9633285/
https://www.ncbi.nlm.nih.gov/pubmed/36087034
http://dx.doi.org/10.1111/cas.15515

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