SHARPIN promotes cell proliferation of cholangiocarcinoma and inhibits ferroptosis via p53/SLC7A11/GPX4 signaling

SHARPIN is a tumor‐associated gene involved in the growth and proliferation of many tumor types. A function of SHARPIN in cholangiocarcinoma (CCA) is so far unclear. Here, we studied the role and function of SHARPIN in CCA and revealed its relevant molecular mechanism. The expression of SHARPIN was...

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Detalles Bibliográficos
Autores principales: Zeng, Chong, Lin, Jie, Zhang, Ketao, Ou, Huohui, Shen, Ke, Liu, Qingbo, Wei, Zibo, Dong, Xinhuai, Zeng, Xiaokang, Zeng, Liming, Wang, Weidong, Yao, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9633309/
https://www.ncbi.nlm.nih.gov/pubmed/35968603
http://dx.doi.org/10.1111/cas.15531

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