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Microdialysis of Drug and Drug Metabolite: a Comprehensive In Vitro Analysis for Voriconazole and Voriconazole N-oxide

PURPOSE: Voriconazole is a therapeutically challenging antifungal drug associated with high interindividual pharmacokinetic variability. As a prerequisite to performing clinical trials using the minimally-invasive sampling technique microdialysis, a comprehensive in vitro microdialysis characterizat...

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Detalles Bibliográficos
Autores principales:	Schulz, Josefine, Michelet, Robin, Zeitlinger, Markus, Mikus, Gerd, Kloft, Charlotte
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2022
Materias:	Original Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9633485/ https://www.ncbi.nlm.nih.gov/pubmed/36171344 http://dx.doi.org/10.1007/s11095-022-03292-0

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