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Treprostinil Supplementation Ameliorates Hepatic Ischemia Reperfusion Injury and Regulates Expression of Hepatic Drug Transporters: An Isolated Perfused Rat Liver (IPRL) Study

PURPOSE: IR injury is an unavoidable consequence in deceased donor liver transplantation. Cold preservation and warm reperfusion may change the expression and function of drug transporters in the liver due to vasoconstriction, infiltration of neutrophils and release of cytokines. We hypothesize that...

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Detalles Bibliográficos
Autores principales: Almazroo, Omar Abdulhameed, Shaik, Imam H, Hughes, Christopher B, Humar, Abhinav, Venkataramanan, Raman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9633539/
https://www.ncbi.nlm.nih.gov/pubmed/36071353
http://dx.doi.org/10.1007/s11095-022-03384-x

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