Epidemiology and Clinical Presentation of COVID-19 in Older Adults

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection remains asymptomatic in 33% to 90% of older adults depending on their immune status from prior infection, vaccination, and circulating strain. Older adults symptomatic with SARS-CoV-2 often both present atypically, such as with a...

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Detalles Bibliográficos
Autores principales: Abul, Yasin, Leeder, Ciera, Gravenstein, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Health Sciences Division 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9633621/
https://www.ncbi.nlm.nih.gov/pubmed/36805007
http://dx.doi.org/10.1016/j.idc.2022.11.001
Descripción
Sumario:Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection remains asymptomatic in 33% to 90% of older adults depending on their immune status from prior infection, vaccination, and circulating strain. Older adults symptomatic with SARS-CoV-2 often both present atypically, such as with a blunted fever response, and develop more severe disease. Early and late reports showed that older adults have increased severity of coronavirus disease 2019 (COVID-19) with higher case fatality rates and higher intensive care needs compared with younger adults. Infection and vaccine-induced antibody response and long-term effects of COVID-19 also differ in older adults.

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