Epidemiology and Clinical Presentation of COVID-19 in Older Adults

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection remains asymptomatic in 33% to 90% of older adults depending on their immune status from prior infection, vaccination, and circulating strain. Older adults symptomatic with SARS-CoV-2 often both present atypically, such as with a...

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Detalles Bibliográficos
Autores principales: Abul, Yasin, Leeder, Ciera, Gravenstein, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Health Sciences Division 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9633621/
https://www.ncbi.nlm.nih.gov/pubmed/36805007
http://dx.doi.org/10.1016/j.idc.2022.11.001
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author Abul, Yasin
Leeder, Ciera
Gravenstein, Stefan
author_facet Abul, Yasin
Leeder, Ciera
Gravenstein, Stefan
author_sort Abul, Yasin
collection PubMed
description Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection remains asymptomatic in 33% to 90% of older adults depending on their immune status from prior infection, vaccination, and circulating strain. Older adults symptomatic with SARS-CoV-2 often both present atypically, such as with a blunted fever response, and develop more severe disease. Early and late reports showed that older adults have increased severity of coronavirus disease 2019 (COVID-19) with higher case fatality rates and higher intensive care needs compared with younger adults. Infection and vaccine-induced antibody response and long-term effects of COVID-19 also differ in older adults.
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spelling pubmed-96336212022-11-04 Epidemiology and Clinical Presentation of COVID-19 in Older Adults Abul, Yasin Leeder, Ciera Gravenstein, Stefan Infect Dis Clin North Am Article Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection remains asymptomatic in 33% to 90% of older adults depending on their immune status from prior infection, vaccination, and circulating strain. Older adults symptomatic with SARS-CoV-2 often both present atypically, such as with a blunted fever response, and develop more severe disease. Early and late reports showed that older adults have increased severity of coronavirus disease 2019 (COVID-19) with higher case fatality rates and higher intensive care needs compared with younger adults. Infection and vaccine-induced antibody response and long-term effects of COVID-19 also differ in older adults. Elsevier Health Sciences Division 2023-03 2022-11-04 /pmc/articles/PMC9633621/ /pubmed/36805007 http://dx.doi.org/10.1016/j.idc.2022.11.001 Text en Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Abul, Yasin
Leeder, Ciera
Gravenstein, Stefan
Epidemiology and Clinical Presentation of COVID-19 in Older Adults
title Epidemiology and Clinical Presentation of COVID-19 in Older Adults
title_full Epidemiology and Clinical Presentation of COVID-19 in Older Adults
title_fullStr Epidemiology and Clinical Presentation of COVID-19 in Older Adults
title_full_unstemmed Epidemiology and Clinical Presentation of COVID-19 in Older Adults
title_short Epidemiology and Clinical Presentation of COVID-19 in Older Adults
title_sort epidemiology and clinical presentation of covid-19 in older adults
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9633621/
https://www.ncbi.nlm.nih.gov/pubmed/36805007
http://dx.doi.org/10.1016/j.idc.2022.11.001
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