Lipopolysaccharide induces placental mitochondrial dysfunction in murine and human systems by reducing MNRR1 levels via a TLR4-independent pathway

Mitochondria play a key role in placental growth and development, and mitochondrial dysfunction is associated with inflammation in pregnancy pathologies. However, the mechanisms whereby placental mitochondria sense inflammatory signals are unknown. Mitochondrial nuclear retrograde regulator 1 (MNRR1...

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Detalles Bibliográficos
Autores principales: Purandare, Neeraja, Kunji, Yusef, Xi, Yue, Romero, Roberto, Gomez-Lopez, Nardhy, Fribley, Andrew, Grossman, Lawrence I., Aras, Siddhesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9633742/
https://www.ncbi.nlm.nih.gov/pubmed/36339251
http://dx.doi.org/10.1016/j.isci.2022.105342

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