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ATP-binding and hydrolysis of human NLRP3

The innate immune system uses inflammasomal proteins to recognize danger signals and fight invading pathogens. NLRP3, a multidomain protein belonging to the family of STAND ATPases, is characterized by its central nucleotide-binding NACHT domain. The incorporation of ATP is thought to correlate with...

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Detalles Bibliográficos
Autores principales:	Brinkschulte, Rebecca, Fußhöller, David M., Hoss, Florian, Rodríguez-Alcázar, Juan F., Lauterbach, Mario A., Kolbe, Carl-Christian, Rauen, Melanie, Ince, Semra, Herrmann, Christian, Latz, Eicke, Geyer, Matthias
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9633759/ https://www.ncbi.nlm.nih.gov/pubmed/36329210 http://dx.doi.org/10.1038/s42003-022-04120-2

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