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Tumor infiltrating CD8/CD103/TIM-3-expressing lymphocytes in epithelial ovarian cancer co-express CXCL13 and associate with improved survival
Reactivation of tumor infiltrating T lymphocytes (TILs) with immune checkpoint inhibitors or co-stimulators has proven to be an effective anti-cancer strategy for a broad range of malignancies. However, epithelial ovarian cancer (EOC) remains largely refractory to current T cell-targeting immunother...
Autores principales: | Vlaming, Martijn, Bilemjian, Vrouyr, Freile, Jimena Álvarez, Melo, Vinicio, Plat, Annechien, Huls, Gerwin, Nijman, Hans W., de Bruyn, Marco, Bremer, Edwin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9633842/ https://www.ncbi.nlm.nih.gov/pubmed/36341460 http://dx.doi.org/10.3389/fimmu.2022.1031746 |
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