Cargando…

Neuromodulation for Management of Chronic Pelvic Pain: A Comprehensive Review

INTRODUCTION: Chronic pelvic pain (CPP) is a symptom that derives from a complex group of heterogeneous pathologies of the pelvic organs. The aim of this study was to review the available evidence on efficacy of neuromodulatory modalities including sacral neuromodulation, dorsal root ganglion stimul...

Descripción completa

Detalles Bibliográficos
Autores principales: Hao, David, Yurter, Alp, Chu, Robert, Salisu-Orhurhu, Mariam, Onyeaka, Henry, Hagedorn, Jon, Patel, Kiran, D’Souza, Ryan, Moeschler, Susan, Kaye, Alan David, Orhurhu, Vwaire
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9633896/
https://www.ncbi.nlm.nih.gov/pubmed/36109459
http://dx.doi.org/10.1007/s40122-022-00430-9
_version_ 1784824343877910528
author Hao, David
Yurter, Alp
Chu, Robert
Salisu-Orhurhu, Mariam
Onyeaka, Henry
Hagedorn, Jon
Patel, Kiran
D’Souza, Ryan
Moeschler, Susan
Kaye, Alan David
Orhurhu, Vwaire
author_facet Hao, David
Yurter, Alp
Chu, Robert
Salisu-Orhurhu, Mariam
Onyeaka, Henry
Hagedorn, Jon
Patel, Kiran
D’Souza, Ryan
Moeschler, Susan
Kaye, Alan David
Orhurhu, Vwaire
author_sort Hao, David
collection PubMed
description INTRODUCTION: Chronic pelvic pain (CPP) is a symptom that derives from a complex group of heterogeneous pathologies of the pelvic organs. The aim of this study was to review the available evidence on efficacy of neuromodulatory modalities including sacral neuromodulation, dorsal root ganglion stimulation, dorsal column neuromodulation, and pudendal nerve stimulation. METHODS: This narrative review focuses on updated information on neuromodulation for management of chronic pelvic pain. In 2022, we searched English-language studies on neuromodulation, pelvic pain, and chronic pain in a comprehensive search. We searched the following databases: PubMed, Medline, SciHub, Cochrane Database of Systematic Reviews, and Google Scholar. We used the following combinations of keywords: neuromodulation, pelvic pain, chronic pain, chronic pelvic pain, pelvic pain treatment. We tried to include as many recent manuscripts as possible (within the last 3 years) but also included papers older than 3 years if they were particularly relevant to our topic. We also attempted to search for, use, and cite primary manuscripts whenever possible. RESULTS: CPP is a challenging entity to treat because of diagnostic inconsistencies and limited evidence for therapeutic modalities. Our review found evidence suggestive of benefit for all modalities reviewed but the data was of overall low quality with numerous limitations. The literature highlights a lack of randomized controlled trials for neuromodulatory therapies but suggests a growing role for such techniques in treating refractory chronic pelvic pain syndrome (CPPS). CONCLUSIONS: This review explores the available evidence on efficacy of neuromodulatory modalities for CPPS and contextualizes the results with information about the type of neuromodulation, lead location and waveform, pain outcomes and assessment timepoints, and reported adverse effects.
format Online
Article
Text
id pubmed-9633896
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Springer Healthcare
record_format MEDLINE/PubMed
spelling pubmed-96338962022-12-07 Neuromodulation for Management of Chronic Pelvic Pain: A Comprehensive Review Hao, David Yurter, Alp Chu, Robert Salisu-Orhurhu, Mariam Onyeaka, Henry Hagedorn, Jon Patel, Kiran D’Souza, Ryan Moeschler, Susan Kaye, Alan David Orhurhu, Vwaire Pain Ther Review INTRODUCTION: Chronic pelvic pain (CPP) is a symptom that derives from a complex group of heterogeneous pathologies of the pelvic organs. The aim of this study was to review the available evidence on efficacy of neuromodulatory modalities including sacral neuromodulation, dorsal root ganglion stimulation, dorsal column neuromodulation, and pudendal nerve stimulation. METHODS: This narrative review focuses on updated information on neuromodulation for management of chronic pelvic pain. In 2022, we searched English-language studies on neuromodulation, pelvic pain, and chronic pain in a comprehensive search. We searched the following databases: PubMed, Medline, SciHub, Cochrane Database of Systematic Reviews, and Google Scholar. We used the following combinations of keywords: neuromodulation, pelvic pain, chronic pain, chronic pelvic pain, pelvic pain treatment. We tried to include as many recent manuscripts as possible (within the last 3 years) but also included papers older than 3 years if they were particularly relevant to our topic. We also attempted to search for, use, and cite primary manuscripts whenever possible. RESULTS: CPP is a challenging entity to treat because of diagnostic inconsistencies and limited evidence for therapeutic modalities. Our review found evidence suggestive of benefit for all modalities reviewed but the data was of overall low quality with numerous limitations. The literature highlights a lack of randomized controlled trials for neuromodulatory therapies but suggests a growing role for such techniques in treating refractory chronic pelvic pain syndrome (CPPS). CONCLUSIONS: This review explores the available evidence on efficacy of neuromodulatory modalities for CPPS and contextualizes the results with information about the type of neuromodulation, lead location and waveform, pain outcomes and assessment timepoints, and reported adverse effects. Springer Healthcare 2022-09-15 2022-12 /pmc/articles/PMC9633896/ /pubmed/36109459 http://dx.doi.org/10.1007/s40122-022-00430-9 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by-nc/4.0/Open AccessThis article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, which permits any non-commercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) .
spellingShingle Review
Hao, David
Yurter, Alp
Chu, Robert
Salisu-Orhurhu, Mariam
Onyeaka, Henry
Hagedorn, Jon
Patel, Kiran
D’Souza, Ryan
Moeschler, Susan
Kaye, Alan David
Orhurhu, Vwaire
Neuromodulation for Management of Chronic Pelvic Pain: A Comprehensive Review
title Neuromodulation for Management of Chronic Pelvic Pain: A Comprehensive Review
title_full Neuromodulation for Management of Chronic Pelvic Pain: A Comprehensive Review
title_fullStr Neuromodulation for Management of Chronic Pelvic Pain: A Comprehensive Review
title_full_unstemmed Neuromodulation for Management of Chronic Pelvic Pain: A Comprehensive Review
title_short Neuromodulation for Management of Chronic Pelvic Pain: A Comprehensive Review
title_sort neuromodulation for management of chronic pelvic pain: a comprehensive review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9633896/
https://www.ncbi.nlm.nih.gov/pubmed/36109459
http://dx.doi.org/10.1007/s40122-022-00430-9
work_keys_str_mv AT haodavid neuromodulationformanagementofchronicpelvicpainacomprehensivereview
AT yurteralp neuromodulationformanagementofchronicpelvicpainacomprehensivereview
AT churobert neuromodulationformanagementofchronicpelvicpainacomprehensivereview
AT salisuorhurhumariam neuromodulationformanagementofchronicpelvicpainacomprehensivereview
AT onyeakahenry neuromodulationformanagementofchronicpelvicpainacomprehensivereview
AT hagedornjon neuromodulationformanagementofchronicpelvicpainacomprehensivereview
AT patelkiran neuromodulationformanagementofchronicpelvicpainacomprehensivereview
AT dsouzaryan neuromodulationformanagementofchronicpelvicpainacomprehensivereview
AT moeschlersusan neuromodulationformanagementofchronicpelvicpainacomprehensivereview
AT kayealandavid neuromodulationformanagementofchronicpelvicpainacomprehensivereview
AT orhurhuvwaire neuromodulationformanagementofchronicpelvicpainacomprehensivereview